Welcome to the Shin Lab!
We study host-pathogen interactions.
In the Shin Lab at the University of Pennsylvania, we are interested in uncovering innate immune mechanisms used by the host to defend itself against bacterial pathogens and how bacterial pathogens evade host immunity to cause disease.
Our most recent work:
Grayczyk, J. P.^, Liu, L.^, Egan, M. S., Aunins, E., Wynosky-Dolfi, M. A., Canna, S. W., Minn, A. J., Shin, S.*, & Brodsky, I. E.* (2024). TLR priming licenses NAIP inflammasome activation by immunoevasive ligands. Proceedings of the National Academy of Sciences of the United States of America, 121(48), e2412700121. Notes: ^co-first authors; *co-corresponding authors.
Our funding:
