Welcome to the Shin Lab!
We study host-pathogen interactions.
In the Shin Lab at the University of Pennsylvania, we are interested in uncovering innate immune mechanisms used by the host to defend itself against bacterial pathogens and how bacterial pathogens evade host immunity to cause disease.
Our most recent work:
Akuma, D. C., Wodzanowski, K. A., Schwartz Wertman, R., Exconde, P. M., Vázquez Marrero, V. R., Odunze, C. E., Grubaugh, D., Shin, S., Taabazuing, C., & Brodsky, I. E. (2024). Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS. eLife, 13, e83725. https://doi.org/10.7554/eLife.83725
Statement of Values
The Shin Lab holds diversity and inclusivity as core values.
We strive to create a supportive, safe, intellectually vibrant, and anti-racist space in which every lab member is seen, and their unique background and contributions are respected and valued. We believe that the advancement of science comes from inclusion of all voices, specifically those that have been systematically marginalized and excluded. We welcome and look forward to working with all individuals regardless of race, religion, gender, gender identity, nationality, disability, or age. We are committed to fostering an inclusive and equitable community in which everyone feels a sense of belonging to be their authentic selves and do their best work.
(Adapted from the Brodsky Lab)
Our funding:
